R-(benzhydryl sulfinyl) acetic acid
(R)-(-)-Modafinil Acid
CAS: 112111-45-2
Molecular Formula: C15H14O3S
R-(benzhydryl sulfinyl) acetic acid - Names and Identifiers
| Name | (R)-(-)-Modafinil Acid |
| Synonyms | (R)-Modanifil acid (R)-(-)-Modafinil Acid (R)-(-)-Modafinic acid (R)-Modafinil Carboxylate R-Benzhydrylsulfinylacetic acid R-(benzhydryl sulfinyl)acetic acid R-(benzhydryl sulfinyl) acetic acid [(diphenylmethyl)sulfinyl]acetic acid 2-[(R)-benzhydrylsulfinyl]acetic acid [(R)-(diphenylmethyl)sulfinyl]acetic acid 2-[(R)-(Diphenyl-methyl)sulfinyl]-acetic Acid Acetic acid, 2-[(R)-(diphenylmethyl)sulfinyl]- |
| CAS | 112111-45-2 |
| InChI | InChI=1/C15H14O3S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H,16,17)/t19-/m1/s1 |
R-(benzhydryl sulfinyl) acetic acid - Physico-chemical Properties
| Molecular Formula | C15H14O3S |
| Molar Mass | 274.33 |
| Density | 1.327 |
| Melting Point | 118-120℃ |
| Boling Point | 539.2±50.0 °C(Predicted) |
| Flash Point | 279.9°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 1.86E-12mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 2.83±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.648 |
R-(benzhydryl sulfinyl) acetic acid - Introduction
R-modafinic acid, also known as (R)-Modafinil acid, is a chiral molecule that is a metabolite of the drug modafinil. The following is a brief introduction to its nature, use, preparation and safety information:
Nature:
R-Modafinic acid is a white or almost white crystal with a melting point of 139-141 degrees Celsius. It is soluble in chloroform and methanol, but insoluble in water. It is an acidic compound.
Use:
R-Modafinic acid is mainly used in drug research and detection. As a metabolite of modafinil, it can be used to determine the metabolic pathway, metabolic rate and excretion mechanism of modafinil in human body.
Preparation Method:
R-Modafinic acid is usually obtained by the metabolic reaction of modafinil. In vivo, modafinil undergoes the action of metabolic enzymes to form its metabolites, including R-modafinil acid. Therefore, researchers can analyze R-modafinil by detecting the metabolites of modafinil in humans.
Safety Information:
There is limited information on the safety and toxicity of R-modafinil acid. Because it is a chemical reagent, it must follow the general chemical laboratory safety procedures. Avoid contact with skin and eyes and maintain adequate ventilation during use. At the same time, it is necessary to properly handle and dispose of the waste of this compound, and to handle the waste according to local regulations. It is best to operate under the guidance of personnel with chemical expertise.
It should be noted that R-modafinic acid is only used for research purposes and is prohibited for medical diagnosis and treatment, and a professional should be consulted before use.
Nature:
R-Modafinic acid is a white or almost white crystal with a melting point of 139-141 degrees Celsius. It is soluble in chloroform and methanol, but insoluble in water. It is an acidic compound.
Use:
R-Modafinic acid is mainly used in drug research and detection. As a metabolite of modafinil, it can be used to determine the metabolic pathway, metabolic rate and excretion mechanism of modafinil in human body.
Preparation Method:
R-Modafinic acid is usually obtained by the metabolic reaction of modafinil. In vivo, modafinil undergoes the action of metabolic enzymes to form its metabolites, including R-modafinil acid. Therefore, researchers can analyze R-modafinil by detecting the metabolites of modafinil in humans.
Safety Information:
There is limited information on the safety and toxicity of R-modafinil acid. Because it is a chemical reagent, it must follow the general chemical laboratory safety procedures. Avoid contact with skin and eyes and maintain adequate ventilation during use. At the same time, it is necessary to properly handle and dispose of the waste of this compound, and to handle the waste according to local regulations. It is best to operate under the guidance of personnel with chemical expertise.
It should be noted that R-modafinic acid is only used for research purposes and is prohibited for medical diagnosis and treatment, and a professional should be consulted before use.
Last Update：2024-04-09 21:32:36
